Gonzalo-Ruiz A, Lieberman A R
Department of Anatomy, School of Physiotherapy, Soria, Spain.
Brain Res Bull. 1995;37(1):17-35. doi: 10.1016/0361-9230(94)00252-5.
We have investigated connections between the thalamic reticular nucleus (TRN) and the anterior thalamic nuclei (ATN) in the rat, following injections of horseradish peroxidase (HRP) into subnuclei of the ATN and different regions of the rostral TRN. Three nonoverlapping groups of neurons in the dorsal part of the ipsilateral rostral TRN project to, and receive reciprocal projections from, specific subnuclei of the ATN. A vertical sheet of neurons in the most dorsal part of the rostral TRN projects to the dorsal half of the posterior subdivision of the anteroventral thalamic nucleus (AVp), the dorsal region of the medial subdivision of the anteroventral thalamic nucleus (AVm), and the dorsolateral part of the rostral anterodorsal thalamic nucleus (AD). Immediately ventral to this part of TRN, but still within its dorsal portion, are a lateral cluster of neurons and a medially located vertical sheet of neurons. The lateral cluster projects to the ventral part of AVp and to the dorsomedial part of rostral AD. The medial sheet projects to the ventral part of AVm, the ventral part of rostral AD, and to the caudal portions of both AV and AD. There appears to be no input to the anteromedial thalamic nucleus (AM) from the TRN. These findings shed new light on the anatomy of the rostral TRN, the ATN, and the connections between the two, and are relevant to emerging hypotheses about the functional organization of the TRN and reticulo-thalamic projections.
我们在大鼠中研究了丘脑网状核（TRN）与前丘脑核（ATN）之间的联系，方法是将辣根过氧化物酶（HRP）注射到ATN的亚核和嘴侧TRN的不同区域。同侧嘴侧TRN背侧的三组不重叠的神经元群投射到ATN的特定亚核，并接受来自这些亚核的相互投射。嘴侧TRN最背侧部分的一层垂直神经元投射到丘脑前腹核后部分（AVp）的背侧半、丘脑前腹核内侧部分（AVm）的背侧区域以及嘴侧丘脑前背核（AD）的背外侧部分。在TRN的这一部分的紧下方，但仍在其背侧部分内，有一群外侧神经元和位于内侧的一层垂直神经元。外侧神经元群投射到AVp的腹侧部分和嘴侧AD的背内侧部分。内侧神经元层投射到AVm的腹侧部分、嘴侧AD的腹侧部分以及AV和AD的尾侧部分。似乎TRN没有向前内侧丘脑核（AM）的输入。这些发现为嘴侧TRN、ATN的解剖结构以及两者之间的联系提供了新的线索，并且与关于TRN和网状丘脑投射功能组织的新假说相关。
