Hulter B M, Lundberg P O
Department of Neurology, University Hospital, Uppsala, Sweden.
J Neurol Neurosurg Psychiatry. 1995 Jul;59(1):83-6. doi: 10.1136/jnnp.59.1.83.
Changes in sexual function in 47 women with advanced multiple sclerosis are described. Twenty eight (59.6%) of the women reported decreased sexual desire. Seventeen (36.2%) reported decreased lubrication. Five (10.6%) others did not know if they lubricated or not. Eighteen women (38.3%) reported diminished orgasmic capacity and six (12.8%) others had never had an orgasm. Sensory dysfunction in the genital area was experienced by 61.7% of the women and 76.6% had weakness of the pelvic muscles. Sixty six per cent had bowel problems and 89.4% had bladder dysfunction. The changes in sexual function correlated both with neurological symptoms from the sacral segments, such as weakness of the pelvic floor and bladder and bowel dysfunction, and to other symptoms such as ataxia and vertigo as well as with age and the occurrence of amenorrhoea. A significant correlation was found between expanded disability status scale (EDSS) score and cohabitation. Problems with sexual function were reported significantly more often by women with lower EDSS scores. Most women (83%) found the interview a positive experience.
本文描述了47名晚期多发性硬化症女性的性功能变化。其中28名（59.6%）女性报告性欲下降。17名（36.2%）报告润滑减少。另有5名（10.6%）女性不清楚自己是否有润滑问题。18名女性（38.3%）报告性高潮能力下降，另有6名（12.8%）女性从未有过性高潮。61.7%的女性经历过生殖器区域感觉功能障碍，76.6%有盆底肌无力。66%有肠道问题，89.4%有膀胱功能障碍。性功能变化与骶段神经症状相关，如盆底肌无力、膀胱和肠道功能障碍，也与共济失调、眩晕等其他症状以及年龄和闭经的发生相关。扩展残疾状态量表（EDSS）评分与同居情况之间存在显著相关性。EDSS评分较低的女性报告性功能问题的频率显著更高。大多数女性（83%）认为此次访谈是一次积极的经历。
