Department of Neurosciences, Reproductive and Odontostomatological Sciences, 'Federico II' University, Naples, Italy.
Neurological Unit, 'S. Filippo' Hospital Rome, Rome, Italy.
Neurol Sci. 2021 Jul;42(7):2903-2910. doi: 10.1007/s10072-020-04873-w. Epub 2020 Nov 21.
People with multiple sclerosis (MS) may experience sexual dysfunction throughout the disease course. Validated scales to assess sexual dysfunction in MS for Italian patients are lacking. Hence, we aimed at validating Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ-19) for Italian MS patients.
We included both male and female MS patients. Each patient completed the Italian translation of the MSISQ-19. Construct validity was explored by the exploratory factor analysis and the Cronbach's alpha coefficient. Test-retest stability and concurrent internal and external validity were examined by Pearson' correlation coefficients.
We enrolled 369 MS patients (323 female and 46 male). Italian MSISQ-19 showed a Cronbach's alpha of 0.92. MSISQ-19 test and retest total scores correlated between each other (r = 0.48, p = 0.01). MSISQ-19 total score also correlated with primary, secondary and tertiary subscales (p < 0.001).
The Italian Version of the MSISQ-19 showed satisfactory internal consistency and reliability with moderately adequate test-retest reproducibility, suggesting that it may be used as a valuable measure of sexual dysfunction in the Italian population.
多发性硬化症（MS）患者可能会在整个疾病过程中经历性功能障碍。缺乏用于评估意大利 MS 患者性功能障碍的经过验证的量表。因此，我们旨在验证多发性硬化症亲密和性功能问卷（MSISQ-19）是否适用于意大利 MS 患者。
我们纳入了男性和女性 MS 患者。每位患者均完成了 MSISQ-19 的意大利语翻译版。通过探索性因素分析和克朗巴赫 α 系数评估结构效度。通过皮尔逊相关系数评估测试-重测稳定性以及同时的内部和外部效度。
我们纳入了 369 名 MS 患者（323 名女性和 46 名男性）。意大利 MSISQ-19 的克朗巴赫 α 系数为 0.92。MSISQ-19 的测试和重测总分相互关联（r = 0.48，p = 0.01）。MSISQ-19 总分也与主要、次要和次要子量表相关（p < 0.001）。
意大利版 MSISQ-19 具有令人满意的内部一致性和可靠性，测试-重测可重复性中等，表明它可作为评估意大利人群性功能障碍的有用工具。
