希腊多发性硬化症女性的性功能障碍：与器质性和心理因素的相关性
Female Sexual Dysfunction Among Greek Women With Multiple Sclerosis: Correlations With Organic and Psychological Factors.
作者信息
Konstantinidis Charalampos, Tzitzika Moira, Bantis Athanasios, Nikolia Archontia, Samarinas Michalis, Kratiras Zisis, Thomas Charalampos, Skriapas Konstantinos
机构信息
Urology & Neuro-urology Unit, National Rehabilitation Center, Ilion, Athens, Greece.
Urology & Neuro-urology Unit, National Rehabilitation Center, Ilion, Athens, Greece.
出版信息
Sex Med. 2019 Mar;7(1):19-25. doi: 10.1016/j.esxm.2018.11.003. Epub 2019 Jan 9.
INTRODUCTION
Multiple Sclerosis (MS) is a degenerative neurological disease that usually occurs between the ages of 20 and 50 years. Sexuality issues are important factors that affect the quality of life of patients.
AIM
To determine and evaluate the prevalence of female sexual dysfunction (FSD) in Greek women with MS and correlate it with organic and psychological factors.
METHODS
248 consecutive women with MS, aged over 18 who admitted to our outpatient clinics from February 2016 to March 2017 were included in the study. Demographics (age, marital status, menopause status, number of children) and disease-related data such as the duration of the disease, Expanded Disability Status Scale (EDSS) and medication for MS obtained.
MAIN OUTCOME MEASURE
All participants completed the Greek validated versions of the Depression, Anxiety, Stress Scale (DASS-21) and the Female Sexual Function Inventory (FSFI) questionnaires. Statistics used to estimate the prevalence of FSD and its correlation with organic (age, EDSS, duration of the disease, menopause status) and psychological factors (depression, anxiety, stress).
RESULTS
FSD was diagnosed in 64.5% of our sample. Age was associated with most subscales of the FSFI. There was no significant correlation in FSFI subscales with the disease duration. Correlation of EDSS and FSFI scores was found to be statistically significant with a negative correlation in all subscales apart from the Satisfaction subscale. Regarding the association between DASS domains and FSFI subscales, there were no significant correlations.
CONCLUSION
FSD is common among Greek women; it is influenced by age, severity of disease, and it is independent of the existence of depression, anxiety, and stress. Konstantinidis C, Tzitzika M, Bantis A, et al. Female sexual dysfunction among Greek women with multiple sclerosis: Correlations with organic and psychological factors. Sex Med 2019;7:19-25.
引言
多发性硬化症（MS）是一种退行性神经疾病，通常发生在20至50岁之间。性问题是影响患者生活质量的重要因素。
目的
确定并评估希腊多发性硬化症女性患者中女性性功能障碍（FSD）的患病率，并将其与器质性和心理因素相关联。
方法
本研究纳入了2016年2月至2017年3月期间在我们门诊就诊的248名年龄超过18岁的连续性多发性硬化症女性患者。收集了人口统计学信息（年龄、婚姻状况、绝经状态、子女数量）以及与疾病相关的数据，如疾病持续时间、扩展残疾状态量表（EDSS）和多发性硬化症用药情况。
主要观察指标
所有参与者均完成了希腊语验证版的抑郁、焦虑、压力量表（DASS - 21）和女性性功能指数（FSFI）问卷。使用统计学方法估计FSD的患病率及其与器质性因素（年龄、EDSS得分、疾病持续时间、绝经状态）和心理因素（抑郁、焦虑、压力）之间的相关性。
结果
我们样本中64.5%的患者被诊断为FSD。年龄与FSFI的大多数子量表相关。FSFI子量表与疾病持续时间之间无显著相关性。除满意度子量表外，EDSS得分与FSFI得分在所有子量表中均呈显著负相关。关于DASS各领域与FSFI子量表之间的关联，未发现显著相关性。
结论
FSD在希腊女性中很常见；它受年龄、疾病严重程度影响，且与抑郁、焦虑和压力的存在无关。康斯坦丁尼迪斯C、齐齐卡M、班蒂斯A等。希腊多发性硬化症女性的女性性功能障碍：与器质性和心理因素的相关性。性医学2019；7：19 - 25。
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