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尼古丁与成瘾。布朗和威廉姆森文件。

Nicotine and addiction. The Brown and Williamson documents.

作者信息

Slade J, Bero L A, Hanauer P, Barnes D E, Glantz S A

机构信息

Department of Medicine, St Peter's Medical Center, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA.

出版信息

JAMA. 1995 Jul 19;274(3):225-33.

PMID:7609231
Abstract

OBJECTIVE

To learn how nicotine has been regarded by a major tobacco company.

DATA SOURCES

Documents from Brown and Williamson Tobacco Corporation (B&W), the British American Tobacco Company (BAT), and other tobacco interests provided by an anonymous source, obtained from Congress, and received from the private papers of a former BAT officer.

STUDY SELECTION

All available materials, including confidential reports regarding research and internal memoranda exchanged between tobacco industry lawyers.

CONCLUSIONS

During a period of 22 years (1962 to 1984), employees of B&W and BAT conducted research and commented on the pharmacology of nicotine. They consistently regarded nicotine as the pharmacological agent that explained tobacco use. In the early part of the period under study, officials of the companies wrote about nicotine addiction explicitly. Inhalation of cigarette smoke by the consumer was recognized throughout the period as necessary for the normal function of a cigarette. The documents contain little indication that research was conducted on either the taste or the flavor of nicotine. The documents reveal an intention on the part of B&W and its corporate parent to affect the function of the body with nicotine.

摘要

目的

了解一家大型烟草公司对尼古丁的看法。

数据来源

由匿名来源提供的来自布朗 & 威廉姆森烟草公司(B&W)、英美烟草公司(BAT)及其他烟草相关机构的文件,这些文件从国会获取,并来自一位前BAT官员的私人文件。

研究选择

所有可得材料,包括有关研究的机密报告以及烟草行业律师之间交换的内部备忘录。

结论

在22年期间(1962年至1984年),B&W和BAT的员工开展了关于尼古丁药理学的研究并进行了评论。他们一直将尼古丁视为解释烟草使用的药理学因素。在研究期间的早期,公司官员明确撰写了关于尼古丁成瘾的内容。在整个期间,消费者吸入香烟烟雾被认为是香烟正常功能所必需的。文件几乎没有表明对尼古丁的味道或风味进行过研究。文件揭示了B&W及其母公司有意利用尼古丁影响身体功能。

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