Takala J, Niemelä N, Rosti J, Sievers K
Circulation. 1979 Mar;59(3):540-3. doi: 10.1161/01.cir.59.3.540.
A 1-year, randomized study was conducted to test the possibility of improving compliance with therapeutic regimens in hypertensives by means of certain simple arrangements. Patients were given written treatment instructions concerning hypertension, a personal blood-pressure follow-up card, and, for those who failed to attend their blood-pressure check-up, an invitation for a new check-up. Using matched pairs, 202 Finnish hypertensives were randomly allocated either to an ordinary or a reorganized treatment group. By means of the latter system, patient compliance could be significantly (p less than 0.01) improved: Only 4% of the patients in this group dropped out of treatment, compared with 19% in the ordinary treatment group. By the end of the year, blood pressure had been lowered by at least 10% in 95% of the patients in the reorganized group and in 78% of those in the ordinary group (p less than 0.01). This was achieved in approximately 60% of cases using chlorthalidone alone.
进行了一项为期1年的随机研究，以测试通过某些简单安排提高高血压患者治疗方案依从性的可能性。向患者提供了有关高血压的书面治疗说明、个人血压随访卡，对于那些未参加血压检查的患者，还发出了新的检查邀请。采用配对法，将202名芬兰高血压患者随机分为普通治疗组或重组治疗组。通过后一种系统，患者的依从性可显著提高（p<0.01）：该组中只有4%的患者退出治疗，而普通治疗组为19%。到年底时，重组组95%的患者血压至少降低了10%，普通组为78%（p<0.01）。在大约60%的病例中，仅使用氯噻酮就实现了这一点。
