Mehregan D A, Vandersteen P, Sikorski L, Mehregan D R
Pinkus Dermatopathology Laboratory, P.C., Monroe, Michigan 48161, USA.
J Am Acad Dermatol. 1995 Aug;33(2 Pt 2):373-5. doi: 10.1016/0190-9622(95)91437-4.
We report two cases of axillary granular parakeratosis, which is a unique eruption involving the axilla that has distinctive histopathologic features. Both of our patients had slightly pruritic, hyperpigmented patches in the axilla. The biopsy specimens revealed severe compact parakeratosis with maintenance of the stratum granulosum and retention of keratohyalin granules throughout the stratum corneum, which was markedly thickened and measured between 90 to 185 microns. The exact etiology is not known, but this conditions is believed to represent a contact reaction to an antiperspirant or deodorant.
我们报告了两例腋窝颗粒状角化不全症，这是一种累及腋窝的独特皮疹，具有独特的组织病理学特征。我们的两位患者腋窝均有轻度瘙痒的色素沉着斑。活检标本显示严重的致密角化不全，颗粒层保留，角质透明颗粒贯穿整个明显增厚的角质层，厚度在90至185微米之间。确切病因尚不清楚，但这种情况被认为是对止汗剂或除臭剂的接触反应。
