MMWR Morb Mortal Wkly Rep. 1995 Jul 28;44(29):545-50.
Before effective vaccines were available, Haemophilus influenzae type b (Hib) was the most common cause of bacterial meningitis among children in the United States. Since the introduction of Hib conjugate vaccines in 1988, the incidence of invasive Hib infection has declined by at least 95% among infants and children (1,2). As part of the Childhood Immunization Initiative (CII), the Public Health Service has included Hib disease among children aged < 5 years as one of the vaccine-preventable diseases targeted for elimination in the United States by 1996 (3). This report summarizes provisional data about invasive Hi disease during 1993-1994 based on information from three surveillance systems: the National Notifiable Diseases Surveillance System (NNDSS), the National Bacterial Meningitis and Bacteremia Reporting System (NBMBRS), and a multistate laboratory-based surveillance system.
在有效疫苗问世之前，b型流感嗜血杆菌（Hib）是美国儿童细菌性脑膜炎最常见的病因。自1988年引入Hib结合疫苗以来，婴儿和儿童侵袭性Hib感染的发病率已下降至少95%（1,2）。作为儿童免疫倡议（CII）的一部分，公共卫生服务部门已将5岁以下儿童的Hib疾病列为到1996年在美国消除的疫苗可预防疾病之一（3）。本报告根据来自三个监测系统的信息，总结了1993 - 1994年期间侵袭性Hi疾病的临时数据：国家法定疾病监测系统（NNDSS）、国家细菌性脑膜炎和菌血症报告系统（NBMBRS）以及一个基于多州实验室的监测系统。
