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向区域中毒控制中心漏报致命病例。

Underreporting of fatal cases to a regional poison control center.

作者信息

Blanc P D, Kearney T E, Olson K R

机构信息

School of Medicine, San Francisco Bay Area Regional Poison Control Center, San Francisco General Hospital, CA, USA.

出版信息

West J Med. 1995 Jun;162(6):505-9.

Abstract

We assessed fatal drug overdose and poisoning case surveillance by a regional poison control center, comparing it with medical examiner determinations of death by poisoning over the same 2-year period and from the same catchment area. We studied 358 fatal cases of poisoning or drug overdose reported by a medical examiner and 10 fatal cases of poisoning or drug overdose reported by a poison control center, analyzing demographics and other case-associated factors with with possible successful poison control center case surveillance. Of the medical examiner cases, 245 (68%) were prehospital deaths. Of the remaining 113 emergency department or hospital cases, only 5 (4.4%) were also reported to the poison control center. Compared with cases involving illicit drugs, other narcotics, and sedative drugs, those that involved other prescription drugs (relative odds, 30.6; 95% confidence interval, 2.7 to 351) and over-the-counter products and other substances (odds ratio, 18.9; 95% confidence interval, 1.4 to 257) were significantly more likely to be reported to the poison control center. Most fatal cases of poisoning and drug overdose are not detected through poison control center surveillance. For prevention and treatment, health planners and policy makers should recognize the implications of case underreporting.

摘要

我们通过一个地区毒物控制中心评估了致命药物过量和中毒病例监测情况,并将其与同一两年期内来自同一集水区的法医判定的中毒死亡情况进行了比较。我们研究了法医报告的358例中毒或药物过量致死病例以及毒物控制中心报告的10例中毒或药物过量致死病例,分析了人口统计学和其他与病例相关的因素,以及毒物控制中心病例监测可能成功的情况。在法医报告的病例中,245例(68%)为院前死亡。在其余113例急诊科或医院病例中,只有5例(4.4%)也报告给了毒物控制中心。与涉及非法药物、其他麻醉药品和镇静药物的病例相比,涉及其他处方药的病例(相对比值,30.6;95%置信区间,2.7至351)以及非处方药和其他物质的病例(比值比,18.9;95%置信区间,1.4至257)更有可能报告给毒物控制中心。大多数中毒和药物过量致死病例未通过毒物控制中心监测发现。为了预防和治疗,卫生规划者和政策制定者应认识到病例报告不足的影响。

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