在溃疡性结肠炎发作期间测定血清蛋白作为患者管理的指导。
Measurement of serum proteins during attacks of ulcerative colitis as a guide to patient management.
作者信息
Buckell N A, Lennard-Jones J E, Hernandez M A, Kohn J, Riches P G, Wadsworth J
出版信息
Gut. 1979 Jan;20(1):22-7. doi: 10.1136/gut.20.1.22.
Abstract
Serial measurements of 11 serum proteins have been made throughout 39 admissions of 36 patients to hospital for the treatment of acute attacks of ulcerative colitis. There was a striking correlation between rapid changes in C-reactive protein and pre-albumin concentrations and the clinical response to medical treatment. Measurements of the alpha1-acid glycoprotein, albumin, and total serum protein concentrations at the time of admission were found to correlate with the outcome of the attack. Measurement of these proteins provides a useful guide to the management of patients with attacks of ulcerative colitis.
摘要
在36例溃疡性结肠炎急性发作患者住院接受治疗的39次入院过程中，对11种血清蛋白进行了连续测量。C反应蛋白和前白蛋白浓度的快速变化与药物治疗的临床反应之间存在显著相关性。入院时α1-酸性糖蛋白、白蛋白和总血清蛋白浓度的测量结果与发作的结局相关。这些蛋白质的测量为溃疡性结肠炎发作患者的管理提供了有用的指导。
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