Volkov V S, Kirilenko N P, Paramonova I V
Klin Lab Diagn. 1995 Mar-Apr(2):32-4.
Red cell stromal lipid fractions (total lipids and phospholipids, triglycerides, free fatty acids, cholesterol and its esters, lisophospholipids, sphyngomyelins, phosphatidylserines, phosphatidylcholines, phosphatidylethanolamines, cardiolipins, phosphatide acids) were measured and ECG A leads at rest analyzed in 29 patients with iron-deficiency anemia to detect myocardial ischemia. Significant changes in red cell stroma lipid composition were revealed, particularly marked in women with myocardial ischemia. Measures aimed at normalization of red cell stromal lipid composition in patients with iron-deficiency anemia may be regarded as one of the factors inhibiting the development of myocardial ischemia.
测定了29例缺铁性贫血患者的红细胞基质脂质成分(总脂质和磷脂、甘油三酯、游离脂肪酸、胆固醇及其酯、溶血磷脂、鞘磷脂、磷脂酰丝氨酸、磷脂酰胆碱、磷脂酰乙醇胺、心磷脂、磷脂酸),并分析了静息时的心电图A导联,以检测心肌缺血情况。结果发现红细胞基质脂质成分有显著变化,在有心肌缺血的女性患者中尤为明显。针对缺铁性贫血患者红细胞基质脂质成分正常化的措施可被视为抑制心肌缺血发展的因素之一。