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[缺铁性贫血患者外周血红细胞的基质脂质与心肌营养不良]

[Stromal lipids of peripheral blood erythrocytes and myocardial dystrophy in patients with iron deficiency anemia].

作者信息

Paramonova I V, Kirilenko N P

出版信息

Gematol Transfuziol. 1993 Jul-Aug;38(7):28-31.

PMID:8307286
Abstract

Lipid fractions (total lipids and phospholipids, triglycerides, free fatty acids, cholesterol, lysophospholipids, sphingomyelins, phosphatidylserines, phosphatidylcholines, phosphatidylethanolamines, cardiolipins, phosphatidic acids) were assessed in stromal red cells of 41 patients with iron deficiency anemia (IDA). The values obtained were correlated with wave T height at rest ECG. It was found that IDA patients have abnormalities in the lipid spectrum of red cell stroma promoting myocardiodystrophy. Therapeutic measures to normalize relevant lipid spectrum may become one of the factors preventing further dystrophic developments in the myocardium.

摘要

对41例缺铁性贫血(IDA)患者的基质红细胞中的脂质成分(总脂质和磷脂、甘油三酯、游离脂肪酸、胆固醇、溶血磷脂、鞘磷脂、磷脂酰丝氨酸、磷脂酰胆碱、磷脂酰乙醇胺、心磷脂、磷脂酸)进行了评估。所获得的值与静息心电图的T波高度相关。发现IDA患者红细胞基质的脂质谱存在异常,这会促进心肌营养不良。使相关脂质谱正常化的治疗措施可能成为预防心肌进一步营养不良发展的因素之一。

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