Anil S, Beena V T, Nair R G, Vijayakumar T
Dental College, Trivandrum, Kerala, India.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jun;79(6):750-2. doi: 10.1016/s1079-2104(05)80311-7.
Serum beta-2-microglobulin was estimated in patients with oral leukoplakia, oral submucous fibrosis, and oral cancer. The results were compared with that of an equal number of age- and sex-matched healthy controls. A definite increase in the level of beta 2-microglobulin was observed in patients with oral submucous fibrosis and oral cancer. Though the level of beta 2-microglobulin was found to be high in oral leukoplakia, it was not statistically significant. Further studies will validate the role of beta 2-microglobulin estimation to predict the malignant potential of oral submucous fibrosis.
对口腔白斑、口腔黏膜下纤维化和口腔癌患者的血清β2-微球蛋白进行了评估。将结果与相同数量年龄和性别匹配的健康对照者的结果进行比较。在口腔黏膜下纤维化和口腔癌患者中观察到β2-微球蛋白水平有明显升高。虽然在口腔白斑中发现β2-微球蛋白水平较高，但无统计学意义。进一步的研究将验证β2-微球蛋白评估在预测口腔黏膜下纤维化恶性潜能方面的作用。
