LaRue J, Bard C, Fleury M, Teasdale N, Paillard J, Forget R, Lamarre Y
Centre de recherche en activités physiques et sportives, Université de Caen, France.
Can J Physiol Pharmacol. 1995 Feb;73(2):255-61. doi: 10.1139/y95-036.
This study tested whether a deafferented patient demonstrates impaired timing ability compared with four control subjects. By comparing normal subjects with the deafferented patient, some insight was expected on the importance of proprioception in timing of motor behavior. The protocol was set to enhance the strategy of the subjects in using feedbacks. Subjects had to synchronize finger taps with a sound produced at regular intervals. Once synchronized, the bips were muted and the subjects had to continue the tapping at the same pace. Interresponse interval (IRI) variability was measured under two feedback conditions: with and without vision and auditory feedback. The Wing and Kristofferson model (A.M. Wing and A.B. Kristofferson. Percept. Psychophys. 13(3): 455-460, 1973) was used to segment IRI variance into separate components: a central clock and a peripheral motor delay. When the deafferented patient saw and heard the outcome of her tapping movements, there was a greater variability in successive intervals between taps than when vison and hearing were blocked. We interpret this variability as indicating that the subject used auditory and visual feedback to maintain a correct overall rhythm. The patient may easily substitute visual and (or) auditory feedback for her defective proprioception for movement timing. However, this substitution proved to be inefficient in the limited training period provided in this experiment. The results suggest that the proprioceptive contribution to the time-keeping mechanism presumably depends on the presence of an efference copy signal.
本研究测试了与四名对照受试者相比，一名传入神经阻滞患者的计时能力是否受损。通过将正常受试者与传入神经阻滞患者进行比较，期望能深入了解本体感觉在运动行为计时中的重要性。实验方案旨在增强受试者使用反馈的策略。受试者必须将手指敲击与定期发出的声音同步。一旦同步，声音就会静音，受试者必须以相同的节奏继续敲击。在两种反馈条件下测量反应间隔（IRI）变异性：有视觉和听觉反馈以及无视觉和听觉反馈。使用温格和克里斯托弗森模型（A.M. Wing和A.B. Kristofferson. Percept. Psychophys. 13(3): 455 - 460, 1973）将IRI方差分为不同成分：一个中央时钟和一个外周运动延迟。当传入神经阻滞患者看到并听到她敲击动作的结果时，敲击之间连续间隔的变异性比视觉和听觉被阻断时更大。我们将这种变异性解释为表明受试者使用听觉和视觉反馈来维持正确的整体节奏。患者可能很容易用视觉和（或）听觉反馈替代其用于运动计时的有缺陷的本体感觉。然而，在本实验提供的有限训练期内，这种替代被证明是低效的。结果表明，本体感觉对计时机制的贡献可能取决于传出副本信号的存在。
