日本肺炎链球菌的抗菌药物耐药性趋势
Trends in antimicrobial resistance of Streptococcus pneumoniae in Japan.
作者信息
Yoshida R, Kaku M, Kohno S, Ishida K, Mizukane R, Takemura H, Tanaka H, Usui T, Tomono K, Koga H
机构信息
Department of Laboratory Medicine, Nagasaki University School of Medicine, Japan.
出版信息
Antimicrob Agents Chemother. 1995 May;39(5):1196-8. doi: 10.1128/AAC.39.5.1196.
Abstract
A total of 184 isolates of Streptococcus pneumoniae were recovered from the sputa of patients over a 5-year period in the Nagasaki area and were examined. A total of 30 strains were resistant to penicillin (MIC, > or = 0.10 micrograms/ml), 13 of which belonged to serotype 19B. These strains showed decreased susceptibility to other antimicrobial agents. Vancomycin, cefpirome, and imipenem were the most active agents tested.
摘要
在长崎地区，5年期间共从患者痰液中分离出184株肺炎链球菌并进行检测。共有30株对青霉素耐药（最低抑菌浓度，≥0.10微克/毫升），其中13株属于19B血清型。这些菌株对其他抗菌药物的敏感性也有所降低。万古霉素、头孢匹罗和亚胺培南是检测中活性最强的药物。
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