Ulbig M W, McHugh D A, McNaught A I, Hamilton A M
Moorfields Eye Hospital, London.
Br J Ophthalmol. 1995 Jun;79(6):569-74. doi: 10.1136/bjo.79.6.569.
The advent of diode lasers has allowed their use in transscleral cyclo photocoagulation for refractory glaucoma. A trial was performed to compare the ocular hypotensive and inflammatory effects of cyclo photocoagulation using a continuous wave diode (810 nm) and a free running neodymium:yttrium aluminium garnet (Nd:YAG) laser (1064 nm).
Forty patients with refractory glaucoma were randomised to receive either diode or Nd:YAG therapy. The intraocular pressure (IOP) and inflammatory response to treatment were monitored over 3 months.
There was no significant laser related difference in the effect on IOP after one treatment. There was, however, a difference in effect in retreatments with the IOP lowering effect significantly less, but equally sustained in diode retreatment patients. Severe postoperative complications such as hyphaema or fibrinous anterior uveitis only occurred in the Nd:YAG group.
The degree and duration of the ocular hypotensive response to cyclo photocoagulation appears to be related to the available power output of the system used, and the extent of tissue damage.
二极管激光器的出现使其可用于难治性青光眼的经巩膜睫状体光凝术。进行了一项试验,以比较使用连续波二极管(810纳米)和自由运转的钕:钇铝石榴石(Nd:YAG)激光器(1064纳米)进行睫状体光凝术的降眼压和炎症效果。
40例难治性青光眼患者被随机分配接受二极管或Nd:YAG治疗。在3个月内监测眼压(IOP)和对治疗的炎症反应。
单次治疗后,在降低眼压的效果方面,激光相关差异不显著。然而,在再次治疗时存在效果差异,二极管再次治疗患者的眼压降低效果明显较小,但同样持续。严重的术后并发症,如前房积血或纤维蛋白性前葡萄膜炎仅发生在Nd:YAG组。
睫状体光凝术降眼压反应的程度和持续时间似乎与所用系统的可用功率输出以及组织损伤程度有关。