Suster S
Arkadi M. Rywlin Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center of Greater Miami, Miami Beach, FL 33140, USA.
Semin Diagn Pathol. 1995 May;12(2):140-57.
Primary pulmonary sarcomas are rare tumors. Because the lung is one of the favored metastatic sites for soft tissue sarcomas, care must be taken when evaluating these lesions to rule out the possibility of an alternate primary source by means of thorough clinical history and radiographic evaluation. In addition to the difficulties involved in separating primary from metastatic tumors, pulmonary sarcomas must be distinguished from a number of sarcomalike primary lung neoplasms, including spindle and giant cell (pleomorphic) carcinoma, and from mixed epithelial/mesenchymal lesions such as pulmonary blastoma and carcinosarcoma. The criteria helpful for accomplishing this distinction are discussed, along with a review of primary sarcomas of the lung, with emphasis on clinicopathologic, immunohistochemical, and ultrastructural features that may be of aid for diagnosis. Additionally, recent or newly described entities are also discussed, and evolving concepts on the pathogenesis and terminology of these lesions are underscored.
原发性肺肉瘤是罕见肿瘤。由于肺是软组织肉瘤常见的转移部位之一，因此在评估这些病变时，必须通过全面的临床病史和影像学评估，谨慎排除其他原发灶的可能性。除了区分原发性肿瘤和转移性肿瘤存在困难外，肺肉瘤还必须与多种肉瘤样原发性肺肿瘤相鉴别，包括梭形细胞癌和巨细胞（多形性）癌，以及与混合性上皮/间叶性病变如肺母细胞瘤和癌肉瘤相鉴别。本文讨论了有助于实现这种鉴别的标准，同时回顾了肺原发性肉瘤，重点阐述了可能有助于诊断的临床病理、免疫组化和超微结构特征。此外，还讨论了近期或新描述的实体，并强调了这些病变在发病机制和术语方面不断演变的概念。
