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精神分裂症和分裂情感性障碍中的慢波睡眠缺陷与预后

Slow-wave sleep deficits and outcome in schizophrenia and schizoaffective disorder.

作者信息

Keshaven M S, Reynolds C F, Miewald J, Montrose D

机构信息

Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA.

出版信息

Acta Psychiatr Scand. 1995 May;91(5):289-92. doi: 10.1111/j.1600-0447.1995.tb09784.x.

DOI:10.1111/j.1600-0447.1995.tb09784.x
PMID:7639083
Abstract

Schizophrenia is associated with altered sleep architecture, particularly in regard to delta sleep. We examined the relation between the baseline polysomnographic measures in schizophrenic and schizoaffective patients and psychosocial outcome as measured by the Strauss & Carpenter scale at 1 (n = 20) and 2 (n = 7) years. The percentages of delta sleep at baseline were significantly correlated with total outcome scores at 1 and at 2 years. These preliminary findings suggest that delta sleep deficits may be associated with relatively poor outcome in this disorder.

摘要

精神分裂症与睡眠结构改变有关,尤其是在慢波睡眠方面。我们研究了精神分裂症和分裂情感性障碍患者的基线多导睡眠图测量值与1年(n = 20)和2年(n = 7)时用施特劳斯和卡彭特量表测量的心理社会结果之间的关系。基线时慢波睡眠的百分比与1年和2年时的总结果得分显著相关。这些初步发现表明,慢波睡眠缺陷可能与该疾病相对较差的预后有关。

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