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大脑中单胺含量的变化会影响情感共鸣反应。

[Changes in the monoamine content of the brain influence the reaction of emotional resonance].

作者信息

Kruglikov R I, Getsova V M, Orlova N V, Lushkina A A, Feshchenko I R

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 May-Jun;45(3):551-7.

PMID:7645330
Abstract

Influence of 5-hydroxytryptophan (5HTP) and disulfiram on a reaction of emotional resonance (RER) was studied in two groups of female rats: I--with good and II--with poor elaboration of RER and, correspondingly, with the minimal and the maximal time of stay in the dark compartment. One week after 5HTP injection good elaboration of RER in animals of the I group was substituted for poor. In the II group of animals RER was unchanged. Injection of disulfiram increased the stay in the dark compartment in the I group and decreased it in the II group. At the same time dopamine content in the midbrain and medulla increased. The results confirm the hypothesis on participation of monoamines and their different contribution in RER realization in different groups of animals.

摘要

在两组雌性大鼠中研究了5-羟色氨酸(5HTP)和双硫仑对情绪共鸣反应(RER)的影响:第一组大鼠RER表现良好,第二组大鼠RER表现较差,相应地,它们在黑暗隔室中的停留时间分别最短和最长。注射5HTP一周后,第一组动物原本良好的RER表现被较差的表现所取代。第二组动物的RER没有变化。注射双硫仑后,第一组动物在黑暗隔室中的停留时间增加,而第二组则减少。与此同时,中脑和延髓中的多巴胺含量增加。结果证实了单胺类物质参与其中以及它们在不同组动物的RER实现中具有不同作用的假设。

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