Denis J, Hery B, Crépin V, Guillemot L, Guerzider P
Service de cardiologie, centre hospitalier général, Saint-Nazaire.
Arch Mal Coeur Vaiss. 1995 Apr;88(4):507-10.
Non-Hodgkin's lymphoma is common in patients with human immuno-deficiency virus infection, but an intracardiac localisation is rare. In this case, the malignant lymphoma presented with a degradation of the patient's condition and signs of right-sided cardiac failure. Echocardiography showed a polylobed mass invading the right ventricle. Computerised tomography provided detailed information of the extension of the lymphoma in the different cardiac chambers. The patient died after a few days of a low cardiac output state. The malignant nature of the tumour was confirmed at biopsy. This case of cardiac lymphoma in a patient with immunodepression confirms the fatal character of this condition in the very short term after the appearance of the first clinical signs, the value of echocardiography in the diagnosis and the difficulty in implementing any effective therapeutic measure.
非霍奇金淋巴瘤在人类免疫缺陷病毒感染患者中很常见,但心脏内定位却很罕见。在该病例中,恶性淋巴瘤表现为患者病情恶化及右侧心力衰竭体征。超声心动图显示一个多叶状肿块侵犯右心室。计算机断层扫描提供了淋巴瘤在不同心腔内扩展的详细信息。患者在出现低心排血量状态几天后死亡。活检证实了肿瘤的恶性性质。该免疫抑制患者发生心脏淋巴瘤的病例证实了这种疾病在出现首批临床症状后短期内的致命性、超声心动图在诊断中的价值以及实施任何有效治疗措施的困难。