Almendingen K, Trygg K, Larsen S, Hofstad B, Vatn M H
Medical Department, Rikshospitalet University Hospital, Oslo, Norway.
Eur J Cancer Prev. 1995 Jun;4(3):239-46. doi: 10.1097/00008469-199506000-00005.
In the case-control study we compared dietary habits among 108 patients with small (< or = 5 mm, n = 26), medium (5-9 mm, n = 48) or large (> or = 10 mm, n = 34) colorectal polyps with 35 healthy age- and gender-matched controls. A food record by weighing during 5 consecutive days was performed. The intake of fat was significantly higher among the patients, in contrast to a significantly lower intake of carbohydrate, dietary fibre and iron, compared with controls. The intake of vitamin C and calcium was shown to be lower among the patients, but this was significant only for women. There was a tendency among the patients to consume a lower-antioxidant, fibre and cereal fibre diet, and a calcium-rich and more cholesterol-rich diet with increasing size of polyps. The patients with the smallest polyps tended to consume less starch. Our results are too preliminary to draw conclusions with regard to the influence of nutritional factors on the size and growth of polyps. However, our risk factors for the presence of polyps are in agreement with previous studies. Further studies taking into account the size of the polyp are needed to corroborate our findings.
在这项病例对照研究中，我们比较了108例患有小（≤5毫米，n = 26）、中（5 - 9毫米，n = 48）或大（≥10毫米，n = 34）结肠直肠息肉的患者与35名年龄和性别匹配的健康对照者的饮食习惯。连续5天进行称重食物记录。与对照组相比，患者的脂肪摄入量显著更高，而碳水化合物、膳食纤维和铁的摄入量则显著更低。患者的维生素C和钙摄入量较低，但仅在女性中具有显著性。随着息肉尺寸增大，患者有摄入抗氧化剂、纤维和谷物纤维含量较低、富含钙和胆固醇较多的饮食的倾向。息肉最小的患者倾向于摄入较少的淀粉。我们的结果过于初步，无法就营养因素对息肉大小和生长的影响得出结论。然而，我们关于息肉存在的风险因素与先前的研究一致。需要进一步考虑息肉大小的研究来证实我们的发现。
