乙型肝炎在健康的乙肝表面抗原阳性母亲中的传播。
Transmission of hepatitis type B from healthy HBsAg-positive mothers.
作者信息
Skinhoj P, Cohn J, Bradburne A F
出版信息
Br Med J. 1976 Jan 3;1(6000):10-11. doi: 10.1136/bmj.1.6000.10.
Abstract
Seventeen mothers, all apparently healthy carriers of hepatitis-B surface antigen (HBsAg) during pregnancy, and their children were studied for four to five years to determine the transmission rate of hepatitis-B virus infection. All the mothers had antibody against hepatitis-B core antigen in addition to HBsAg. One of them, a renal transplant recipient, was persistently positive for hepatitis-B-associated e antigen (HBeAg), while the remaining 16, who were detected during screening of healthy pregnant women were positive for anti-HBe. Evidence of infection was found in the child and husband of the woman positive for HBeAg, while none of the 29 children and five husbands of the anti-HBe-positive women became infected.
摘要
对17名母亲及其子女进行了4至5年的研究，以确定乙肝病毒感染的传播率。这些母亲在怀孕期间均显然是乙肝表面抗原（HBsAg）的健康携带者。所有母亲除了有HBsAg外，还具有抗乙肝核心抗原抗体。其中一名母亲是肾移植受者，乙肝e抗原（HBeAg）持续呈阳性，而其余16名在健康孕妇筛查中被检测出的母亲抗-HBe呈阳性。HBeAg呈阳性的女性的孩子及其丈夫发现了感染证据，而抗-HBe呈阳性的女性的29名孩子和5名丈夫均未感染。
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