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[钩端螺旋体病与妊娠。法属圭亚那的11例病例]

[Leptospirosis and pregnancy. Eleven cases in French Guyana].

作者信息

Carles G, Montoya E, Joly F, Peneau C

机构信息

Service de Gynécologie-Obstétrique, Centre Hospitalier André-Bouron, Saint-Laurent-du-Maroni, Guyane Française.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1995;24(4):418-21.

PMID:7650320
Abstract

The incidence of leptospirosis, a widespread antropozoonosis, is underestimated due to variable clinical presentations. The abortive effect of this disease, well known in animals, is only reported rarely in humans although transplacental transmission has been demonstrated. We report 11 cases of leptospirosis in pregnant women in French Guiana. The diagnosis was made on identification of the germ in maternal urine samples and/or on specific serology tests. Fetal death occurred in more than 50% of the cases due to premature abortion or in utero death. The rate of maternal-fetal transmissions is not known, but leptospirosis could be a not uncommon cause of perinatal deaths in endemic zones.

摘要

钩端螺旋体病是一种广泛存在的人畜共患病,由于临床表现多样,其发病率被低估。这种疾病在动物中广为人知的流产效应,尽管已经证实存在经胎盘传播,但在人类中很少有报道。我们报告了法属圭亚那11例孕妇钩端螺旋体病病例。诊断是通过在母体尿液样本中鉴定病原体和/或进行特异性血清学检测做出的。超过50%的病例因早产或宫内死亡导致胎儿死亡。母婴传播率尚不清楚,但钩端螺旋体病可能是流行地区围产期死亡的一个常见原因。

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