Scholl T O, Hediger M L, Schall J I, Ances I G, Smith W K
Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, Camden, USA.
Obstet Gynecol. 1995 Sep;86(3):423-7. doi: 10.1016/0029-7844(95)00190-3.
To determine whether the risk of maternal overweight associated with an excessive rate of gestational gain needs to be balanced against the risks of impaired fetal growth associated with a low rate of gain.
Rate of gestational weight gain was measured prospectively in a sample of 274 young, low-income, and primarily minority women (12-29 years old) with pregravid body mass indices (BMI) in the normal range (19.8-26.0). We defined an excessive rate of gain between 20-36 weeks' gestation as one greater than 0.68 kg/week, and a low rate of gain as one less than 0.34 kg/week. Women were followed-up at 4-6 weeks and 6 months postpartum.
Rate of measured gestational gain between 20-36 weeks' gestation was associated with total weight gain based on pregravid weight, with infant birth weight and gestation duration, and with maternal overweight (BMI greater than 26) and weight retention postpartum. Infant birth weight and gestation duration were significantly reduced for women with low rates of gain, and there was no significant difference between women with excessive and moderate gains. Despite little difference in pregravid BMI, women with excessive rates of gain retained more weight overall, attained a greater postpartum BMI, and had higher levels of subcutaneous fat and overweight. Maternal anthropometric status showed little change between 4-6 weeks and 6 months postpartum.
Weight gained at an excessive rate by women with a pregravid BMI in the normal range does not greatly enhance fetal growth and gestation duration, contributing instead to postpartum maternal overweight.
确定与孕期体重增加过快相关的孕妇超重风险是否需要与孕期体重增加过慢相关的胎儿生长受限风险相权衡。
前瞻性测量了274名年轻、低收入且主要为少数族裔的女性(年龄12 - 29岁)的孕期体重增加率,这些女性孕前体重指数(BMI)在正常范围内(19.8 - 26.0)。我们将妊娠20 - 36周期间体重增加过快定义为每周增加超过0.68千克,体重增加过慢定义为每周增加少于0.34千克。在产后4 - 6周和6个月对这些女性进行随访。
妊娠20 - 36周期间测得的体重增加率与基于孕前体重的总体重增加、婴儿出生体重和妊娠期时长相关,也与孕妇超重(BMI大于26)及产后体重保留相关。体重增加过慢的女性其婴儿出生体重和妊娠期时长显著降低,体重增加过快和适中的女性之间无显著差异。尽管孕前BMI差异不大,但体重增加过快的女性总体上保留的体重更多,产后BMI更高,皮下脂肪水平更高且超重。孕妇人体测量学状态在产后4 - 6周和6个月之间变化不大。
孕前BMI在正常范围内的女性体重增加过快并不会显著促进胎儿生长和延长妊娠期,反而会导致产后孕妇超重。