Lo C Y, Chan D T, Yuen K Y, Li F K, Cheng K P
Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam.
Lupus. 1995 Jun;4(3):229-31. doi: 10.1177/096120339500400313.
We describe a patient with SLE who was infected by the fungus Penicillium marneffei. She was initially misdiagnosed as having disseminated tuberculosis. The correct diagnosis was finally made by bone marrow culture and she responded to a prolonged course of amphotericin B, flucytosine and itraconazole. The clinical presentation and histology of penicilliosis are very similar to those of Mycobacterium tuberculosis. In Southeast Asia, penicilliosis should be considered as a differential diagnosis in patients with SLE who present with fever and lymphadenopathy.
我们描述了一名系统性红斑狼疮（SLE）患者，她感染了马尔尼菲青霉菌。她最初被误诊为播散性肺结核。最终通过骨髓培养做出了正确诊断，她对长期使用两性霉素B、氟胞嘧啶和伊曲康唑的疗程有反应。青霉病的临床表现和组织学与结核分枝杆菌感染非常相似。在东南亚，对于出现发热和淋巴结病的SLE患者，应将青霉病视为鉴别诊断之一。
