Leng J, Yang X, Yang N
Peking Union Medical College Hospital, Beijing.
Zhonghua Fu Chan Ke Za Zhi. 1995 Apr;30(4):218-21.
Through catheter on uterine artery digital subtractive angiography (DSA) intraarterial infusion of chemotherapeutic agents for the treatment of malignant trophoblastic diseases can raise local drug concentration, improve therapeutic results and reduce general side-effects. But mural thrombosis, a possible complication of intra arterial catheterization, should not be overlooked. This study reports 2 cases of mural thrombosis complication in selective pelvic artery catheterization for chemotherapy. The incidence, relevant factors to its occurrence such as technique of catheterization and the duration of catheter retention, as well as measures of prevention and treatment of mural thrombosis are discussed together with review of literature. With regards to prevention of mural thrombosis, stress is being laid on the importance of the technique of catheterization. Preliminary comments on the problem of heparin administration as a preventive measure of mural thrombosis are made.
通过子宫动脉数字减影血管造影（DSA）导管进行动脉内化疗药物灌注治疗恶性滋养细胞疾病，可提高局部药物浓度，改善治疗效果并减少全身副作用。但动脉内插管可能的并发症——壁血栓形成，不容忽视。本研究报告了2例在选择性盆腔动脉插管化疗中发生壁血栓形成并发症的病例。结合文献复习，讨论了其发生率、发生的相关因素如插管技术和导管留置时间，以及壁血栓形成的防治措施。关于壁血栓形成的预防，强调了插管技术的重要性。对作为壁血栓形成预防措施的肝素给药问题作了初步评论。
