• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Isolation and characterization of a naturally occurring parainfluenza 3 virus variant.一种天然存在的副流感3型病毒变体的分离与鉴定
J Clin Microbiol. 1995 Jul;33(7):1839-41. doi: 10.1128/jcm.33.7.1839-1841.1995.
2
Rapid detection of parainfluenza virus type 3 RNA in respiratory specimens: use of reverse transcription-PCR-enzyme immunoassay.呼吸道标本中副流感病毒3型RNA的快速检测：逆转录-聚合酶链反应-酶免疫测定法的应用
J Clin Microbiol. 1994 Feb;32(2):484-8. doi: 10.1128/jcm.32.2.484-488.1994.
3
Nucleotide and deduced amino acid sequence of hemagglutinin-neuraminidase genes of human type 3 parainfluenza viruses isolated from 1957 to 1983.1957年至1983年分离的人3型副流感病毒血凝素-神经氨酸酶基因的核苷酸及推导的氨基酸序列
Virology. 1988 Jan;162(1):137-43. doi: 10.1016/0042-6822(88)90402-3.
4
Nucleotide sequence of the coding and flanking regions of the human parainfluenza virus 3 hemagglutinin-neuraminidase gene: comparison with other paramyxoviruses.人副流感病毒3型血凝素-神经氨酸酶基因编码区及侧翼区域的核苷酸序列：与其他副粘病毒的比较。
Intervirology. 1987;27(2):69-80. doi: 10.1159/000149722.
5
Development and evaluation of NucliSens basic kit NASBA for diagnosis of parainfluenza virus infection with 'end-point' and 'real-time' detection.用于副流感病毒感染诊断的采用“终点法”和“实时”检测的NucliSens基础试剂盒核酸序列扩增技术的开发与评估
J Virol Methods. 2003 Mar;108(2):145-55. doi: 10.1016/s0166-0934(02)00268-9.
6
Human parainfluenza type 3 virus hemagglutinin-neuraminidase glycoprotein: nucleotide sequence of mRNA and limited amino acid sequence of the purified protein.人副流感3型病毒血凝素-神经氨酸酶糖蛋白：mRNA的核苷酸序列及纯化蛋白的有限氨基酸序列
J Virol. 1986 Feb;57(2):481-9. doi: 10.1128/JVI.57.2.481-489.1986.
7
Establishment of reverse transcription polymerase chain reaction assay for simultaneous detection of human parainfluenza virus types 1 to 4 in children with influenza like illnesses.建立用于同时检测流感样疾病患儿中1至4型人副流感病毒的逆转录聚合酶链反应检测法。
Bratisl Lek Listy. 2017;118(12):772-776. doi: 10.4149/BLL_2017_145.
8
Genetic variation and evolution of human parainfluenza virus type 1 hemagglutinin neuraminidase: analysis of 12 clinical isolates.1型人副流感病毒血凝素神经氨酸酶的遗传变异与进化：12株临床分离株的分析
J Infect Dis. 1992 Nov;166(5):995-1005. doi: 10.1093/infdis/166.5.995.
9
Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK.英国3型人副流感病毒分离株血凝素-神经氨酸酶基因的序列变异
Epidemiol Infect. 1995 Jun;114(3):493-500. doi: 10.1017/s0950268800052201.
10
Molecular cloning and sequence analysis of the human parainfluenza 3 virus genes encoding the surface glycoproteins, F and HN.编码表面糖蛋白F和HN的人副流感3病毒基因的分子克隆及序列分析
Virus Res. 1987 Sep;8(3):205-15. doi: 10.1016/0168-1702(87)90016-5.

引用本文的文献

1
Complete genome sequence and pathogenicity of two swine parainfluenzavirus 3 isolates from pigs in the United States.美国猪源两株副流感病毒 3 型的全基因组序列与致病性分析
J Virol. 2010 Jan;84(2):686-94. doi: 10.1128/JVI.00847-09. Epub 2009 Nov 11.
2
The common cold: a review of the literature.普通感冒：文献综述
Eur J Intern Med. 2004 Apr;15(2):79-88. doi: 10.1016/j.ejim.2004.01.006.
3
A sensitive, specific, and cost-effective multiplex reverse transcriptase-PCR assay for the detection of seven common respiratory viruses in respiratory samples.一种用于检测呼吸道样本中七种常见呼吸道病毒的灵敏、特异且经济高效的多重逆转录聚合酶链反应检测方法。
J Mol Diagn. 2004 May;6(2):125-31. doi: 10.1016/S1525-1578(10)60500-4.
4
Rapid and sensitive method using multiplex real-time PCR for diagnosis of infections by influenza a and influenza B viruses, respiratory syncytial virus, and parainfluenza viruses 1, 2, 3, and 4.一种使用多重实时聚合酶链反应的快速灵敏方法，用于诊断甲型和乙型流感病毒、呼吸道合胞病毒以及1、2、3和4型副流感病毒感染。
J Clin Microbiol. 2004 Apr;42(4):1564-9. doi: 10.1128/JCM.42.4.1564-1569.2004.
5
Direct detection of respiratory syncytial virus, parainfluenza virus, and adenovirus in clinical respiratory specimens by a multiplex reverse transcription-PCR assay.通过多重逆转录聚合酶链反应法直接检测临床呼吸道标本中的呼吸道合胞病毒、副流感病毒和腺病毒。
J Clin Microbiol. 1998 Nov;36(11):3149-54. doi: 10.1128/JCM.36.11.3149-3154.1998.
6
Simultaneous detection and identification of human parainfluenza viruses 1, 2, and 3 from clinical samples by multiplex PCR.通过多重聚合酶链反应从临床样本中同时检测和鉴定人副流感病毒1、2和3型
J Clin Microbiol. 1998 May;36(5):1388-91. doi: 10.1128/JCM.36.5.1388-1391.1998.
7
Two distinct human parainfluenza virus type 1 genotypes detected during the 1991 Milwaukee epidemic.1991年密尔沃基疫情期间检测到两种不同的人类1型副流感病毒基因型。
J Clin Microbiol. 1996 Mar;34(3):695-700. doi: 10.1128/jcm.34.3.695-700.1996.

本文引用的文献

1
Rapid detection of parainfluenza virus type 3 RNA in respiratory specimens: use of reverse transcription-PCR-enzyme immunoassay.呼吸道标本中副流感病毒3型RNA的快速检测：逆转录-聚合酶链反应-酶免疫测定法的应用
J Clin Microbiol. 1994 Feb;32(2):484-8. doi: 10.1128/jcm.32.2.484-488.1994.
2
Parainfluenza viral infections in pediatric outpatients: seasonal patterns and clinical characteristics.
Pediatr Infect Dis J. 1994 Apr;13(4):269-73. doi: 10.1097/00006454-199404000-00005.
3
Polymer support oligonucleotide synthesis XVIII: use of beta-cyanoethyl-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product.聚合物载体寡核苷酸合成 XVIII：脱氧核苷的β-氰基乙基-N，N-二烷基氨基-/N-吗啉代亚磷酰胺用于 DNA 片段合成，简化最终产物的脱保护和分离
Nucleic Acids Res. 1984 Jun 11;12(11):4539-57. doi: 10.1093/nar/12.11.4539.
4
Production of monoclonal antibodies against parainfluenza 3 virus and their use in diagnosis by immunofluorescence.抗副流感3病毒单克隆抗体的制备及其在免疫荧光诊断中的应用。
J Clin Microbiol. 1985 Oct;22(4):535-8. doi: 10.1128/jcm.22.4.535-538.1985.
5
Evaluation of two immunofluorescence assays with monoclonal antibodies for typing of herpes simplex virus.用单克隆抗体对两种免疫荧光法进行单纯疱疹病毒分型的评估。
J Clin Microbiol. 1985 Apr;21(4):643-4. doi: 10.1128/jcm.21.4.643-644.1985.
6
Nucleotide and deduced amino acid sequence of hemagglutinin-neuraminidase genes of human type 3 parainfluenza viruses isolated from 1957 to 1983.1957年至1983年分离的人3型副流感病毒血凝素-神经氨酸酶基因的核苷酸及推导的氨基酸序列
Virology. 1988 Jan;162(1):137-43. doi: 10.1016/0042-6822(88)90402-3.
7
Molecular cloning and sequence analysis of the human parainfluenza 3 virus genes encoding the surface glycoproteins, F and HN.编码表面糖蛋白F和HN的人副流感3病毒基因的分子克隆及序列分析
Virus Res. 1987 Sep;8(3):205-15. doi: 10.1016/0168-1702(87)90016-5.
8
Nucleotide sequence of the coding and flanking regions of the human parainfluenza virus 3 hemagglutinin-neuraminidase gene: comparison with other paramyxoviruses.人副流感病毒3型血凝素-神经氨酸酶基因编码区及侧翼区域的核苷酸序列：与其他副粘病毒的比较。
Intervirology. 1987;27(2):69-80. doi: 10.1159/000149722.
9
Comparison of monoclonal antibody time-resolved fluoroimmunoassay with monoclonal antibody capture-biotinylated detector enzyme immunoassay for respiratory syncytial virus and parainfluenza virus antigen detection.单克隆抗体时间分辨荧光免疫测定法与单克隆抗体捕获-生物素化检测酶免疫测定法用于呼吸道合胞病毒和副流感病毒抗原检测的比较。
J Clin Microbiol. 1989 Jun;27(6):1243-9. doi: 10.1128/jcm.27.6.1243-1249.1989.
10
Antigenic and structural properties of the hemagglutinin-neuraminidase glycoprotein of human parainfluenza virus type 3: sequence analysis of variants selected with monoclonal antibodies which inhibit infectivity, hemagglutination, and neuraminidase activities.人副流感病毒3型血凝素-神经氨酸酶糖蛋白的抗原性和结构特性：用抑制感染性、血凝和神经氨酸酶活性的单克隆抗体筛选的变异体序列分析
J Virol. 1987 May;61(5):1473-7. doi: 10.1128/JVI.61.5.1473-1477.1987.

一种天然存在的副流感3型病毒变体的分离与鉴定

Isolation and characterization of a naturally occurring parainfluenza 3 virus variant.

作者信息

Swierkosz E M, Erdman D D, Bonnot T, Schneiderheinze C, Waner J L

机构信息

Department of Pediatrics, St. Louis University School of Medicine, MO 63104, USA.

出版信息

J Clin Microbiol. 1995 Jul;33(7):1839-41. doi: 10.1128/jcm.33.7.1839-1841.1995.

DOI:10.1128/jcm.33.7.1839-1841.1995
PMID:7665656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC228281/
Abstract

A parainfluenza 3 virus variant which failed to react with parainfluenza 3 virus-specific monoclonal anti-bodies from two commercial sources was isolated from a 14-month-old boy. Analysis of the coding region of the hemagglutinin-neuraminidase gene identified 36 nucleotide changes and 4 amino acid changes compared with a consensus sequence derived from strains isolated from 1957 through 1983. Two unique amino acid changes occurred at positions 174 and 283, which are close to identified epitopes in the hemagglutinin-neuraminidase protein. Ongoing viral surveillance to detect variants is important, particularly in regard to vaccine development.

摘要

从一名14个月大的男孩体内分离出一种副流感3病毒变体，该变体与来自两个商业来源的副流感3病毒特异性单克隆抗体不发生反应。与1957年至1983年分离出的毒株的共有序列相比，对血凝素神经氨酸酶基因编码区的分析确定了36个核苷酸变化和4个氨基酸变化。在174和283位发生了两个独特的氨基酸变化，这两个位置靠近血凝素神经氨酸酶蛋白中已确定的表位。持续进行病毒监测以检测变体很重要，特别是对于疫苗研发而言。