Huang M E, Chuat J C, Galibert F
UPR41-CNRS Recombinaisons Génétiques, Faculté de Médecine, Rennes, France.
Yeast. 1995 Jun 30;11(8):775-81. doi: 10.1002/yea.320110809.
We have sequenced a 42,500 bp stretch located on chromosome X of Saccharomyces cerevisiae between the genes MET3 and CDC8. This stretch contains 24 open reading frames (ORFs) of at least 100 amino acids. Ten of these correspond to previously published sequences, whereas of the 14 remaining ORFs, only one, GTD892, has significant similarity to proteins from yeast or other organisms. It may belong to the family of ubiquitin-protein ligases and be involved in the ubiquitin-dependent proteolytic pathway. In addition, three tRNA genes were recognized, two of which had not been hitherto localized.
我们对酿酒酵母X染色体上位于MET3基因和CDC8基因之间的一段42,500 bp的序列进行了测序。这段序列包含24个至少有100个氨基酸的开放阅读框（ORF）。其中10个与先前发表的序列相对应，而其余14个ORF中，只有一个GTD892与酵母或其他生物体的蛋白质有显著相似性。它可能属于泛素-蛋白连接酶家族，并参与泛素依赖性蛋白水解途径。此外，还识别出三个tRNA基因，其中两个此前尚未定位。
