Brodribb A J, Humphreys D M
Br Med J. 1976 Feb 21;1(6007):425-8. doi: 10.1136/bmj.1.6007.425.
Forty patients with diverticular disease were treated with wheat bran 24g/day for at least six months. Thirty-three patients showed a very satisfactory clinical response. Sixty per cent of all symptoms were abolished, and a further 28% were relieved. After treatment the transit times accelerated in patients whose initial times were slower than 60 hours and slowed down in those whose initial transit times were faster than 36 hours. Stool weight increased significantly. The number of intracolonic high pressure waves decreased, especially during and after eating. Barium enema studies showed less spasm in eight patients and no diverticula in three patients after taking bran. As well as relieving the symptoms of diverticular disease a high-fibre diet may also prevent the condition from developing.
40例憩室病患者接受每日24克麦麸治疗，疗程至少6个月。33例患者临床反应非常令人满意。所有症状的60%消失，另有28%得到缓解。治疗后，初始转运时间慢于60小时的患者转运时间加快，而初始转运时间快于36小时的患者转运时间减慢。粪便重量显著增加。结肠内高压波数量减少，尤其是在进食期间和进食后。钡剂灌肠研究显示，8例患者服用麸皮后痉挛减轻，3例患者无憩室。高纤维饮食除了能缓解憩室病症状外，还可能预防该病的发生。
