De Stefani E, Oreggia F, Rivero S, Ronco A, Fierro L
Registro Nacional de Cáncer, Instituto Nacional de Oncología, Montevideo, Uruguay.
Eur J Epidemiol. 1995 Apr;11(2):177-80. doi: 10.1007/BF01719484.
A hospital-based, case-control study of laryngeal cancer was conducted in the Oncology Institute, Montevideo, Uruguay, during 1988-1992, in which 143 new cases and 460 controls were interviewed. The study was restricted to males. As in most previous studies tobacco smoking and alcohol drinking were the major risk factors. Past and current salted meat consumption was associated with increased risks of laryngeal cancer, after controlling for the effects of tobacco and alcohol. Cigarette smoking and consumption of salted meat appeared to increase the risk of laryngeal cancer in a multiplicative fashion. Fresh meat consumption (beef) was also associated with an increased risk of laryngeal cancer (OR 2.0). After controlling for fresh meat ingestion, the estimates for salted meat remained significant.
1988年至1992年期间,在乌拉圭蒙得维的亚肿瘤研究所开展了一项基于医院的喉癌病例对照研究,共对143例新发病例和460例对照进行了访谈。该研究仅限于男性。与大多数先前的研究一样,吸烟和饮酒是主要的危险因素。在控制了烟草和酒精的影响后,过去和现在食用咸肉与喉癌风险增加有关。吸烟和食用咸肉似乎以相乘的方式增加喉癌风险。食用新鲜肉类(牛肉)也与喉癌风险增加有关(比值比为2.0)。在控制了新鲜肉类摄入后,咸肉的估计风险仍然显著。