Giroud M, Dumas R
Neurology Service, General Hospital, University of Burgondy, Dijon, France.
J Neurol Neurosurg Psychiatry. 1995 Sep;59(3):238-42. doi: 10.1136/jnnp.59.3.238.
A prospective clinical and radiological correlation study was performed to determine the frequency, and the clinical and radiological features of callosal infarction. From 1 January 1993 to the end of December 1993 282 cases of cerebral infarction seen in the Neurology service of the University Hospital of Dijon were studied prospectively. Eight cases with callosal ischaemic lesions were identified by CT and MRI. A callosal disconnection syndrome occurred in only five of eight patients, related to a single, large infarct or several infarctions in the anterior part of the corpus callosum. Clinical features were characterised by left ideomotor apraxia, construction apraxia, and left agraphia in all five cases. Alien hand was noted in only two cases. There were gait disorders in three cases with MRI features of multiple lacunes in a large part of the corpus callosum, and also the subcortical areas of both hemispheres. It is emphasised that callosal infarctions are not rare and that they contribute to the clinical features of strokes. As well as the classic incomplete callosal disconnection syndrome, these callosal ischaemic lesions may induce non-specific gait disorders.
进行了一项前瞻性临床与影像学相关性研究，以确定胼胝体梗死的发生率、临床及影像学特征。1993年1月1日至1993年12月底，对第戎大学医院神经科收治的282例脑梗死患者进行了前瞻性研究。通过CT和MRI确定了8例胼胝体缺血性病变患者。8例患者中仅有5例出现胼胝体离断综合征，与胼胝体前部单个大梗死灶或多个梗死灶有关。所有5例患者的临床特征均表现为左侧观念运动性失用、结构性失用和左侧失写症。仅2例患者出现异己手现象。3例患者存在步态障碍，MRI显示胼胝体大部分及双侧半球皮质下区域有多个腔隙性梗死灶。需要强调的是，胼胝体梗死并不罕见，且对中风的临床特征有影响。除了典型的不完全胼胝体离断综合征外，这些胼胝体缺血性病变还可能导致非特异性步态障碍。
