Mathew P, Teasdale G, Bannan A, Oluoch-Olunya D
Department of Neurosurgery, Southern General Hospital, Glasgow, Scotland, UK.
J Neurol Neurosurg Psychiatry. 1995 Sep;59(3):287-92. doi: 10.1136/jnnp.59.3.287.
The clinical features, treatment, and outcome were reviewed for 48 patients with a haematoma and 71 patients with an infarct in the posterior fossa in order to develop a rational plan of management. Clinical features alone were insufficient to make a diagnosis in about half of the series. Patients with a haematoma were referred more quickly to the neurosurgical unit, were more often in coma, and more often had CT evidence of brain stem compression and acute hydrocephalus. Ultimately, 75% of the patients with a haematoma required an operation. By contrast, most patients with an infarct were managed successfully conservatively. Early surgical management in both cerebellar haemorrhage and infarct (either external ventricular drainage or evacuation of the lesion), associated with early presentation and CT signs of brain stem compression and acute hydrocephalus, led to a good outcome in most patients. Of the patients with cerebellar haematoma initially treated by external drainage, over half subsequently required craniectomy and evacuation of the lesion; but, in some cases, this failed to reverse the deterioration. In patients with a cerebellar infarct, external drainage was more often successful. The guidelines, findings, and recommendations for future management of patients with posterior fossa stroke are discussed.
回顾了48例后颅窝血肿患者和71例梗死患者的临床特征、治疗方法及预后,以制定合理的治疗方案。仅依靠临床特征,在约一半的病例中不足以做出诊断。血肿患者被更快地转诊至神经外科,昏迷的比例更高,且更常出现脑干受压和急性脑积水的CT证据。最终,75%的血肿患者需要手术治疗。相比之下,大多数梗死患者保守治疗成功。小脑出血和梗死的早期手术治疗(包括脑室外引流或病变清除),若伴有早期就诊以及脑干受压和急性脑积水的CT表现,大多数患者可获得良好预后。最初接受脑室外引流治疗的小脑血肿患者中,超过一半随后需要颅骨切除术和病变清除术;但在某些情况下,这未能扭转病情恶化。在小脑梗死患者中,脑室外引流更常取得成功。文中还讨论了后颅窝卒中患者未来治疗的指南、研究结果及建议。