Orkin M, Maibach H I
Department of Dermatology, University of Minnesota, Robbinsdale.
Semin Dermatol. 1993 Mar;12(1):22-5.
The addition of permethrin as a scabicide with low toxicity adds significantly to our therapeutic options for typical and special forms of scabies. Detailed specific management suggestions, as well as a scabies instruction sheet, are included. The management of crusted (Norwegian) scabies and scabies in human immunodeficiency virus-acquired immune deficiency syndrome (HIV/AIDS) is more difficult and may require, particularly in those intensely immunosuppressed, repeated treatment with scabicides and sometimes sequential use of several agents. Tolerance (resistance) to lindane was suggested in Central America but also in South America, Haiti, Egypt, and in clusters in the United States.
添加毒性较低的氯菊酯作为杀疥剂，极大地增加了我们针对典型和特殊形式疥疮的治疗选择。文中包含了详细的具体管理建议以及一份疥疮说明书。结痂性（挪威型）疥疮和人类免疫缺陷病毒获得性免疫缺陷综合征（HIV/AIDS）患者的疥疮管理更为困难，尤其对于那些免疫功能严重受抑制的患者，可能需要反复使用杀疥剂治疗，有时还需依次使用多种药物。中美洲以及南美洲、海地、埃及和美国的一些地区都曾出现对林丹的耐受性（耐药性）情况。
