Krammer H J, Karahan S T, Mayer B, Zhang M, Kühnel W
Department of Anatomy, Medical University of Lübeck, Germany.
Ann Anat. 1993 Jun;175(3):225-30. doi: 10.1016/s0940-9602(11)80006-3.
This study analyses the occurrence of NOS-immunoreactive neurons in the enteric nervous system of the porcine small intestine, and particularly their distribution pattern in the ganglia of the two submucosal plexuses, the external submucosal plexus and the internal submucosal plexus. Numerous NOS-immunoreactive nerve cell bodies were found in the external submucosal plexus, as well as in the myenteric plexus. In 1 cm2 of the surface of the submucosal whole-mount preparation, we counted 186 NOS-immunoreactive nerve cell bodies in the external submucosal plexus, which is about 27% of the total number of nerve cells in that plexus. As against this, we found only very few NOS-immunoreactive nerve cells in the internal submucosal plexus. In the external submucosal plexus, these cells are often located together, forming aggregates within the ganglia. NOS-immunoreactive nerve cells are of different sizes and shapes. Some of them have a multidendritic uniaxonal appearance. NOS-immunoreactive nerve fibres can be observed in all three ganglionic networks, surrounding NOS-immunoreactive as well as nonimmunoreactive nerve cell bodies and forming varicosities in close proximity to the nerve cell bodies.
本研究分析了猪小肠肠神经系统中一氧化氮合酶（NOS）免疫反应性神经元的发生情况，特别是它们在两个黏膜下神经丛，即外黏膜下神经丛和内黏膜下神经丛的神经节中的分布模式。在外黏膜下神经丛以及肌间神经丛中发现了大量NOS免疫反应性神经细胞体。在黏膜下整装标本1平方厘米的表面，我们在外黏膜下神经丛中计数到186个NOS免疫反应性神经细胞体，约占该神经丛神经细胞总数的27%。与此相反，我们在内黏膜下神经丛中仅发现极少数NOS免疫反应性神经细胞。在外黏膜下神经丛中，这些细胞常常聚集在一起，在神经节内形成细胞团。NOS免疫反应性神经细胞大小和形状各异。其中一些具有多树突单轴突的外观。在所有三个神经节网络中均可观察到NOS免疫反应性神经纤维，它们围绕着NOS免疫反应性和非免疫反应性神经细胞体，并在靠近神经细胞体的部位形成膨体。
