Tortosa C G, Vargas M L, Cámara M, Alemán P, Montes M J, Ruiz C, Olivares E G
Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Granada, Spain.
Virchows Arch A Pathol Anat Histopathol. 1993;423(4):287-90. doi: 10.1007/BF01606892.
The expression of adhesion molecules by endothelial cells (EC) of early human decidua was studied with monoclonal antibodies and the immunoperoxidase technique. Although E-selectin, INCAM-110 and VCAM-1 were poorly detected on decidual EC, ICAM-1, P-selectin and DR antigens were highly expressed by these cells, some of which showed high endothelial venule-like morphology. Our results suggest that decidual EC are activated, and are probably involved in the active recruitment of leucocytes.
利用单克隆抗体和免疫过氧化物酶技术，研究了人早期蜕膜内皮细胞（EC）黏附分子的表达情况。虽然在蜕膜EC上很难检测到E-选择素、INCAM-110和VCAM-1，但这些细胞高表达ICAM-1、P-选择素和DR抗原，其中一些细胞呈现出高内皮微静脉样形态。我们的结果表明，蜕膜EC被激活，可能参与白细胞的主动募集。
