Positive interference of merthiolate in the TDx digoxin assay in control samples used in the Belgian External Quality Assessment (EQA) Scheme.
作者信息
Devleeschouwer N, Libeer J C, Schiettecatte J, Maes V, Demolder J, Debusschere P M, Gorus F
机构信息
Department of Clinical Biology, Institut of Hygiene and Epidemiology, Brussels, Belgium.
出版信息
Eur J Clin Chem Clin Biochem. 1994 Dec;32(12):935-7.
PMID:7696443
Abstract
We investigated the possible origin of the spuriously high results observed with the Abbott TDx Immunoassay in the 1991 Belgian external quality assessment scheme for digoxin. The present work ascribes this discrepancy to a matrix effect induced by the addition of merthiolate as preservative to the control samples. It consequently stresses the importance of avoiding the use of this compound for preparing such samples.
摘要
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