Devleeschouwer N, Libeer J C, Schiettecatte J, Maes V, Demolder J, Debusschere P M, Gorus F
Department of Clinical Biology, Institut of Hygiene and Epidemiology, Brussels, Belgium.
Eur J Clin Chem Clin Biochem. 1994 Dec;32(12):935-7.
We investigated the possible origin of the spuriously high results observed with the Abbott TDx Immunoassay in the 1991 Belgian external quality assessment scheme for digoxin. The present work ascribes this discrepancy to a matrix effect induced by the addition of merthiolate as preservative to the control samples. It consequently stresses the importance of avoiding the use of this compound for preparing such samples.
我们调查了在1991年比利时地高辛外部质量评估计划中，使用雅培TDx免疫测定法观察到的假性高结果的可能来源。目前的研究将这种差异归因于在对照样品中添加硫柳汞作为防腐剂所引起的基质效应。因此，它强调了避免使用这种化合物来制备此类样品的重要性。
