检测肠道对念珠菌属分泌性免疫球蛋白A反应的方法及其在人类免疫缺陷病毒感染的慢性腹泻患者中的初步应用。
Methods for detection of an intestinal secretory immunoglobulin A response to Candida spp. and their preliminary application in human immunodeficiency virus-infected patients with chronic diarrhea.
作者信息
Scerpella E G, Gould S S, Mathewson J J, DuPont H L
机构信息
Center for Infectious Diseases, University of Texas Medical School, Houston.
出版信息
Clin Diagn Lab Immunol. 1995 Mar;2(2):246-8. doi: 10.1128/cdli.2.2.246-248.1995.
Abstract
Six of 11 human immunodeficiency virus (HIV)-infected patients with chronic diarrhea, shedding only Candida spp. in their stools, elicited a Candida-specific secretory immunoglobulin A response. Similar responses were identified in only 1 of 10 HIV-positive patients with chronic diarrhea but without Candida spp. and in none of 10 HIV-negative subjects without diarrhea. Candida spp. may play a role in the etiology of chronic diarrhea associated with HIV infection.
摘要
11名感染人类免疫缺陷病毒（HIV）且患有慢性腹泻的患者中，有6名患者粪便中仅排出念珠菌属，他们产生了念珠菌特异性分泌型免疫球蛋白A反应。在10名患有慢性腹泻但粪便中无念珠菌属的HIV阳性患者中，只有1名出现了类似反应，而10名无腹泻的HIV阴性受试者中无人出现此类反应。念珠菌属可能在与HIV感染相关的慢性腹泻病因中起作用。
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