Egan R M, Munn R K
Department of Internal Medicine, University of Kentucky Medical Center, Lexington 40536.
J Rheumatol. 1994 Dec;21(12):2376-9.
We describe the case of a 25-year-old woman who presented with the antiphospholipid antibody syndrome (APS) manifesting as hemolytic anemia, thrombocytopenia, renal insufficiency, thromboses in multiple sites including skin, spleen and nasal mucosa, and multiple sites of avascular necrosis of bone. Interestingly, she also had low grade disseminated intravascular coagulation, which has been suggested to be a mechanism for avascular necrosis. We suggest that the APS may be one cause of thrombosis in avascular necrosis.
我们描述了一名25岁女性的病例，该患者患有抗磷脂抗体综合征（APS），表现为溶血性贫血、血小板减少、肾功能不全、包括皮肤、脾脏和鼻粘膜在内的多个部位血栓形成，以及多处骨缺血性坏死。有趣的是，她还存在轻度弥散性血管内凝血，这被认为是骨缺血性坏死的一种机制。我们认为APS可能是骨缺血性坏死中血栓形成的原因之一。
