Satrija F, Nansen P, Bjørn H, Murtini S, He S
Danish Centre for Experimental Parasitology, Department of Veterinary Microbiology, Royal Veterinary and Agricultural University, Frederiksberg.
J Helminthol. 1994 Dec;68(4):343-6. doi: 10.1017/s0022149x00001619.
An experiment was carried out to investigate the anthelmintic activity of papaya latex (Carica papaya) against natural infection of Ascaris suum in pigs. Sixteen naturally infected pigs were, on the basis of faecal egg counts and body weight, allocated into four groups, each of four pigs. Three groups (groups B, C, and D) were given papaya latex per os at dose levels of 2, 4, and 8 g of papaya latex per kg body weight, respectively. The fourth group (group A) served as a non-treated control. Results of post mortem counts on day 7 post treatment revealed worm count reductions of 39.5, 80.1 and 100% in groups B, C, and D, respectively. Some of the pigs receiving the highest dose of the latex showed mild diarrhoea on the day following treatment. Otherwise, no clinical or pathological changes were observed in the treated animals. The possible future use of this traditional herbal medicine for livestock and humans is discussed.
开展了一项实验,以研究木瓜乳胶(番木瓜)对猪自然感染猪蛔虫的驱虫活性。根据粪便虫卵计数和体重,将16头自然感染的猪分为四组,每组四头猪。三组(B组、C组和D组)分别按每公斤体重2克、4克和8克木瓜乳胶的剂量口服给予木瓜乳胶。第四组(A组)作为未处理的对照。治疗后第7天的尸检计数结果显示,B组、C组和D组的蠕虫计数分别减少了39.5%、80.1%和100%。一些接受最高剂量乳胶的猪在治疗后的第二天出现了轻度腹泻。否则,在接受治疗的动物中未观察到临床或病理变化。讨论了这种传统草药未来在牲畜和人类中的可能用途。