Eamsila C, Frances S P, Strickman D
Research Division, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
J Am Mosq Control Assoc. 1994 Dec;10(4):515-21.
A trial to compare the effect of military clothing treated by high-pressure spray with permethrin or placebo on the incidence of malaria in Royal Thai Army troops was conducted in northeastern Thailand. Bioassays of treated clothing using laboratory-reared Anopheles dirus females showed permethrin remained in the treated fabric for up to 90 days. Both permethrin- and placebo-treated uniform shirts provided > 84% protection from biting An. dirus in laboratory bioassays for the duration of the study. In laboratory tests, knockdown of An. dirus exposed to permethrin-treated cloth fell to < 20% after 3 hand washes, despite the presence of 28.7-59.9% of the original dose of permethrin. The use of permethrin-treated uniforms without adjunct application of topical repellents did not reduce malaria in Thai troops in an operational setting where incidence during 6 months was as high as 412 cases/1,000 in spite of chemoprophylaxis and use of untreated bednets.
在泰国东北部进行了一项试验，比较用氯菊酯或安慰剂高压喷雾处理的军装对泰国皇家军队士兵疟疾发病率的影响。使用实验室饲养的雌性大劣按蚊对处理过的衣物进行生物测定，结果显示氯菊酯在处理过的织物中可保留长达90天。在整个研究期间，经氯菊酯和安慰剂处理的制服衬衫在实验室生物测定中对大劣按蚊叮咬的防护率均>84%。在实验室测试中，经氯菊酯处理的布料，即使仍存在28.7 - 59.9%的原始氯菊酯剂量，在3次手洗后，暴露于其上的大劣按蚊击倒率降至<20%。在一个行动环境中，尽管进行了化学预防并使用了未处理的蚊帐，但6个月期间发病率高达412例/1000人，在此情况下，使用经氯菊酯处理的制服且未额外使用局部驱虫剂，并未降低泰国军队中的疟疾发病率。
