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从纳米比亚迁至南非的桑人(布须曼人)的血液学状况。

Haematological condition of the San (Bushmen) relocated from Namibia to South Africa.

作者信息

Coetzee M J, Badenhorst P N, de Wet J I, Joubert G

机构信息

Department of Haematology, University of the Orange Free State, Bloemfontein.

出版信息

S Afr Med J. 1994 Jul;84(7):416-20.

PMID:7709307
Abstract

A cross-sectional study was undertaken to assess the haematological condition of the San (Bushmen) relocated from Namibia to South Africa. We studied 238 subjects--145 men and 93 women; none of the women was pregnant. We performed full blood counts and estimations of serum vitamin B12, folate, ferritin and erythrocyte folate concentrations. The mean haemoglobin concentration among the men was 14.7 g/dl and 19 (13%) were anaemic; among the women it was 13.8 g/dl and 18 (19%) were anaemic. Thirteen (9%) of the men and 22 (24%) of the women had low concentrations of serum ferritin, and 38 (26%) of the men and 22 (24%) of the women had erythrocyte folate concentrations of less than 270 nmol/l. Three (2%) men and 4 (4%) women had serum vitamin B12 concentrations of less than 120 pmol/l. Eighty-one (56%) of the men and 76 (82%) of the women had eosinophilia, probably because of parasitic infections. It would appear from this and previous studies that prolonged exposure of these hunter-gatherers to a Western lifestyle has resulted in a high prevalence of anaemia, caused by low iron and folate intakes, complicated by alcohol consumption.

摘要

开展了一项横断面研究,以评估从纳米比亚迁移至南非的桑人(布须曼人)的血液学状况。我们研究了238名受试者,其中145名男性和93名女性,所有女性均未怀孕。我们进行了全血细胞计数,并测定了血清维生素B12、叶酸、铁蛋白和红细胞叶酸浓度。男性的平均血红蛋白浓度为14.7 g/dl,19人(13%)贫血;女性的平均血红蛋白浓度为13.8 g/dl,18人(19%)贫血。13名男性(9%)和22名女性(24%)的血清铁蛋白浓度较低,38名男性(26%)和22名女性(24%)的红细胞叶酸浓度低于270 nmol/l。3名男性(2%)和4名女性(4%)的血清维生素B12浓度低于120 pmol/l。81名男性(56%)和76名女性(82%)嗜酸性粒细胞增多,可能是由于寄生虫感染。从这项研究以及之前的研究来看,这些狩猎采集者长期接触西方生活方式导致贫血患病率较高,原因是铁和叶酸摄入量低,并因饮酒而加重。

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