Done S H, Paton D J
Central Veterinary Laboratory, New Haw, Addlestone, Surrey.
Vet Rec. 1995 Jan 14;136(2):32-5. doi: 10.1136/vr.136.2.32.
Porcine reproductive and respiratory syndrome (PRRS) was first known as blue-eared pig disease in the United Kingdom and the causative agent as 'Lelystad virus'. The disease is characterised by very variable clinical signs, including reproductive failure and respiratory disease. The respiratory syndrome is often associated with severe infection with secondary bacterial agents including Pasteurella multocida, Haemophilus parasuis and Streptococcus suis. However, some seropositive herds show no clinical signs of disease. The secondary infections may be facilitated by the destruction of circulating lymphocytes, by the destruction of the mucociliary clearance system and, most importantly, by a large reduction in the numbers of alveolar macrophages. The clinical syndrome observed in a herd may therefore depend in part upon the other diseases present.
猪繁殖与呼吸综合征（PRRS）在英国最初被称为蓝耳病，其病原体为“莱利斯塔德病毒”。该疾病的临床症状变化很大，包括繁殖障碍和呼吸道疾病。呼吸道综合征通常与继发细菌感染有关，这些细菌包括多杀性巴氏杆菌、副猪嗜血杆菌和猪链球菌。然而，一些血清学阳性猪群并无疾病的临床症状。循环淋巴细胞的破坏、黏液纤毛清除系统的破坏，以及最重要的肺泡巨噬细胞数量的大幅减少，可能会促使继发感染。因此，一个猪群中观察到的临床综合征可能部分取决于其他并存的疾病。
