Yao M Y, Xiao S H, Feng J J, Xue C L, Shimada M
Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine.
Zhongguo Yao Li Xue Bao. 1994 Nov;15(6):521-4.
Eighteen and 23 FAA components were detected in the cyst wall and cyst fluid of E granulosus, respectively, by using automatic amino acid analyzer. The concentrations of most of the determined FAA were higher in the cyst fluid than those in the cyst wall, especially the taurine was 5-fold higher. Mebendazole treatment resulted in an increase in the concentration of alanine, valine, lysine, and taurine in both cyst wall and cyst fluid, the most notable being the alanine in the cyst wall. The results are interpreted as a coupling of glycolysis and amino acid metabolism, suggesting an involvement of FAA metabolism in the mechanism of Meb action.
使用自动氨基酸分析仪分别在细粒棘球绦虫的囊壁和囊液中检测到18种和23种游离氨基酸（FAA）成分。所测定的大多数FAA在囊液中的浓度高于囊壁中的浓度，尤其是牛磺酸高出5倍。甲苯咪唑处理导致囊壁和囊液中丙氨酸、缬氨酸、赖氨酸和牛磺酸的浓度增加，最显著的是囊壁中的丙氨酸。这些结果被解释为糖酵解与氨基酸代谢的耦合，表明FAA代谢参与了甲苯咪唑作用机制。
