Debicki P S, Okoniewski M, Okoniewska E, Shrivastava P N, Debicka A M, Baert L V, Petrovich Z
Department of Radiation Oncology, University of Southern California, School of Medicine, Kenneth Norris Cancer Hospital, Los Angeles 90033.
Int J Hyperthermia. 1995 Jan-Feb;11(1):95-108. doi: 10.3109/02656739509004951.
A new intracavitary applicator design for microwave hyperthermia, particularly for transrectal prostate treatment, is presented. It includes an exchangeable multisection antenna that enables us to create a required longitudinal heating pattern, a cooling system to shift the maximum temperature away from the surface and a microwave reflecting system embedded in the cooling system that allows one to shape the irradiation beam in a transverse direction. Independent control of the longitudinal and transverse irradiation patterns of the applicator along with the cooling system, enable precise heating of selected tissues. Results of SAR measurements, E-field measurements and steady state temperature distributions, in solid and liquid tissue-equivalent phantoms are presented. Clinical performance of this applicator was evaluated earlier in patients heated intraoperatively and in a phase I clinical study. The applicator was found capable of effectively heating a tissue volume extending radially 3-25 mm from the applicator surface, angularly defined by configuration of reflecting system and longitudinally determined by specific choice of the multisection antenna.
本文介绍了一种用于微波热疗的新型腔内施源器设计，特别是用于经直肠前列腺治疗。它包括一个可更换的多节天线，使我们能够创建所需的纵向加热模式；一个冷却系统，用于将最高温度从表面移开；以及一个嵌入冷却系统的微波反射系统，该系统允许在横向方向上塑造照射束。施源器的纵向和横向照射模式与冷却系统的独立控制，能够精确加热选定的组织。文中给出了在固体和液体组织等效体模中的比吸收率（SAR）测量、电场测量和稳态温度分布的结果。该施源器的临床性能在早期的术中加热患者和I期临床研究中进行了评估。结果发现，该施源器能够有效地加热从施源器表面径向延伸3 - 25毫米的组织体积，其角度由反射系统的配置定义，纵向由多节天线的特定选择确定。
