Ono S, Chida K, Takasu T
Department of Neurology, Nihon University, Surugadai Hospital, Tokyo.
Intern Med. 1994 Dec;33(12):799-801. doi: 10.2169/internalmedicine.33.799.
Guillain-Barré syndrome (GBS) developed soon after the onset of acute viral hepatitis A (HA) in a 62-year-old man. GBS associated with HA is extremely rare, even though HA is common. In a review of case reports the clinical features of GBS following HA could be summarized as follows: 1) Most of the patients are men. 2) GBS develops within 14 days after the onset of HA. 3) Facial nerve palsy is frequently present. 4) Proprioception is likely impaired in addition to superficial sensation. 5) The outcome of neuropathic symptoms is uniformly good, regardless of the degree of liver dysfunction as evaluated on the basis of alanine aminotransferase levels. These findings indicate that GBS following HA essentially does not differ from typical GBS.
一名62岁男性在急性甲型肝炎（HA）发病后不久即出现吉兰 - 巴雷综合征（GBS）。尽管HA很常见，但与HA相关的GBS极为罕见。在对病例报告的回顾中，HA后GBS的临床特征可总结如下：1）大多数患者为男性。2）GBS在HA发病后14天内出现。3）常出现面神经麻痹。4）除浅感觉外，本体感觉可能受损。5）无论根据丙氨酸转氨酶水平评估的肝功能障碍程度如何，神经病变症状的预后均一致良好。这些发现表明，HA后的GBS本质上与典型GBS并无不同。
