Ashinoff R, Levine V J, Soter N A
Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York 10016, USA.
Dermatol Surg. 1995 Apr;21(4):291-4. doi: 10.1111/j.1524-4725.1995.tb00175.x.
Cutaneous allergic reactions to pigments found in tattoos are not infrequent. Cinnabar (mercuric sulfide) is the most common cause of allergic reactions in tattoos and is probably related to a cell-mediated (delayed) hypersensitivity reaction.
The purpose of these case presentations is to describe a previously unreported complication of tattoo removal with two Q-switched lasers.
Two patients without prior histories of skin disease experienced localized as well as widespread allergic reactions after treatment of their tattoos with two Q-switched lasers.
The Q-switched ruby and neodymium:yttrium-aluminum-garnet lasers target intracellular tattoo pigment, causing rapid thermal expansion that fragments pigment-containing cells and causes the pigment to become extracellular. This extracellular pigment is then recognized by the immune system as foreign.
对纹身中色素的皮肤过敏反应并不罕见。朱砂（硫化汞）是纹身过敏反应最常见的原因，可能与细胞介导的（迟发性）超敏反应有关。
这些病例报告的目的是描述一种此前未报道的用两种调Q激光去除纹身的并发症。
两名既往无皮肤病史的患者在用两种调Q激光治疗纹身后出现了局部及广泛的过敏反应。
调Q红宝石激光和钕：钇铝石榴石激光作用于细胞内的纹身色素，引起快速的热膨胀，使含色素的细胞破碎，导致色素进入细胞外。然后，这种细胞外色素被免疫系统识别为外来物质。
