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病毒感染:甲型病毒所致关节病

Viral infections: alpha-viral arthropathy.

作者信息

McGill P E

机构信息

Stobhill Hospital NHS Trust, Glasgow, UK.

出版信息

Baillieres Clin Rheumatol. 1995 Feb;9(1):145-50. doi: 10.1016/s0950-3579(05)80151-7.

Abstract

Six different mosquito-borne viruses (Chikungunya, O'nyong-nyong, Mayaro, Ross River, Sindbis and Barmah Forest) have been associated with arthritis in humans. These viruses are prevalent in the tropics and subtropics and they produce similar symptoms, consisting of fever, joint pains and rash. The symptoms are usually of short duration, around 1 week; complete recovery is the rule apart from exceptional cases of Chik infection. Precise diagnosis requires a serological service which is not available in many parts of the tropics these days. Treatment is symptomatic and there is no vaccine currently available. With an increasing number of visitors to the tropics being exposed to potential infection and with rapid air transport it is possible that visitors may return home during the viraemic incubation stage, infect the local mosquito populations and then develop clinical disease.

摘要

六种不同的蚊媒病毒(基孔肯雅病毒、奥尼昂尼昂病毒、马亚罗病毒、罗斯河病毒、辛德毕斯病毒和巴马森林病毒)已被证实与人类关节炎有关。这些病毒在热带和亚热带地区流行,它们会引发相似的症状,包括发热、关节疼痛和皮疹。症状通常持续时间较短,约为1周;除了基孔肯雅病毒感染的特殊病例外,一般都能完全康复。准确诊断需要血清学检测服务,而如今在热带地区的许多地方都无法提供这种服务。治疗以对症治疗为主,目前尚无可用疫苗。随着前往热带地区的游客接触潜在感染的人数不断增加,以及航空运输的快速发展,游客有可能在病毒血症潜伏期回国,感染当地的蚊虫种群,随后出现临床疾病。

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