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种族与乳腺癌生存的预后意义:一种评估所报告生存差异可靠性的模型

The prognostic significance of race and survival from breast cancer: a model for assessing the reliability of reported survival differences.

作者信息

Roach M, Alexander M

机构信息

Dept of Radiation Oncology, University of California, San Francisco 94143-0226, USA.

出版信息

J Natl Med Assoc. 1995 Mar;87(3):214-9.

PMID:7731072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2607822/
Abstract

For more than 20 years, black women with breast cancer have been reported to have a lower survival rate than white women with breast cancer. Despite correcting for stage and socioeconomic status, some studies continue to report race-related excess mortality. A reliability scoring system was developed, based primarily on the precision of the staging system used, and the likelihood that the quality of treatment was comparable. Studies that compared the survival of blacks and whites treated for breast cancer from 1968 to 1988 were included in this study. Studies that demonstrated relatively large differences in the 5-year survival between blacks and whites were associated with low reliability scores. Studies that reported little or no difference in 5-year survival rates were associated with relatively high reliability scores. This model and the literature on which it is based suggest that the reported survival differences associated with race can be explained by differences in stage at presentation and by differences in the quality of care received. Efforts directed at early detection and improvements in the quality of care delivered are likely to reduce the excess breast cancer mortality experienced by black women.

摘要

20多年来,据报道,患有乳腺癌的黑人女性的生存率低于患有乳腺癌的白人女性。尽管对疾病分期和社会经济地位进行了校正,但一些研究仍继续报告与种族相关的超额死亡率。开发了一种可靠性评分系统,主要基于所使用的分期系统的精确性以及治疗质量具有可比性的可能性。本研究纳入了1968年至1988年期间比较接受乳腺癌治疗的黑人和白人患者生存率的研究。那些显示黑人和白人5年生存率存在相对较大差异的研究,其可靠性评分较低。那些报告5年生存率几乎没有差异或没有差异的研究,其可靠性评分相对较高。该模型及其所依据的文献表明,所报告的与种族相关的生存差异可以通过就诊时的分期差异以及所接受护理质量的差异来解释。针对早期检测和提高所提供护理质量的努力,可能会降低黑人女性所经历的超额乳腺癌死亡率。

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本文引用的文献

1
Measuring racial bias in inpatient treatment.衡量住院治疗中的种族偏见。
Am J Psychiatry. 1980 Jun;137(6):679-82. doi: 10.1176/ajp.137.6.679.
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Survival of cancer patients by economic status in a free care setting.在免费医疗环境下按经济状况划分的癌症患者生存率
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Social class and black-white differences in breast cancer survival.社会阶层与乳腺癌生存率的黑白差异。
Am J Public Health. 1986 Dec;76(12):1400-3. doi: 10.2105/ajph.76.12.1400.
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The interaction of estrogen receptor status and race in predicting prognosis for stage I breast cancer patients.雌激素受体状态与种族在预测I期乳腺癌患者预后中的相互作用。
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