de Meester C, Gerber G B
Université Catholique de Louvain, Faculté de Médecine, Département de Pharmacie, Bruxelles, Belgique.
Rev Epidemiol Sante Publique. 1995;43(2):147-61.
The paper reviews the epidemiological studies that investigate the relationships between dietary protein intake and the risk of some cancer and that have been published since 1980. A comparison of these reports is complicated because of many confounding factors that could obscure the conclusions (e.g. choice of controls) and because it is difficult to distinguish the consumption of fat from that of animal proteins. The 75 examined publications deal with the influence of food intake on different cancers: colo-rectal (42), stomach (8), breast (7), ovarian (4), endometrium (3), prostate (4), pancreas (2), urothelium (1), bladder (2), brain (1), lymphoma (1). From these studies in parallel with information from other sources, it is concluded that pyrolysis products generated by heat treatment of protein-rich food could be responsible factors for, at least, colo-rectal cancer.
本文回顾了自1980年以来发表的关于调查膳食蛋白质摄入量与某些癌症风险之间关系的流行病学研究。由于许多可能掩盖结论的混杂因素（如对照的选择），以及难以区分脂肪与动物蛋白的摄入量，这些报告的比较变得复杂。所审查的75篇出版物探讨了食物摄入对不同癌症的影响：结直肠癌（42篇）、胃癌（8篇）、乳腺癌（7篇）、卵巢癌（4篇）、子宫内膜癌（3篇）、前列腺癌（4篇）、胰腺癌（2篇）、尿路上皮癌（1篇）、膀胱癌（2篇）、脑癌（1篇）、淋巴瘤（1篇）。从这些研究以及其他来源的信息可以得出结论，富含蛋白质食物热处理产生的热解产物可能至少是结直肠癌的致病因素。
