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委陵菜中的原花青素:分离及其对超氧阴离子自由基清除活性的研究

Procyanidins from tormentil: fractionation and study of the anti-radical activity towards superoxide anion.

作者信息

Vennat B, Bos M A, Pourrat A, Bastide P

机构信息

Laboratoire de Pharmacie Galénique et Pharmacotechnie Industrielle, UFR Pharmacie, Clermont-Ferrand, France.

出版信息

Biol Pharm Bull. 1994 Dec;17(12):1613-5. doi: 10.1248/bpb.17.1613.

Abstract

A standardised water-soluble extract was prepared from rhizomes of Potentilla tormentilla. The procyanidins in the extract were fractionated according to their degree of polymerisation by chromatography on Sephadex LH20. The anti-radical activities of the different fractions towards superoxide anion were compared when pentamers and hexamers were found to be the most active.

摘要

从委陵菜的根茎中制备了标准化的水溶性提取物。提取物中的原花青素通过在葡聚糖LH20上进行色谱分离,根据其聚合度进行分级。当发现五聚体和六聚体具有最强活性时,比较了不同级分对超氧阴离子的抗自由基活性。

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